There might be a possibility of this happening, if hints inside the companion app are to be believed. Rockstar Games fan site Rockstar Intel found inside the files for the app multiple parameters that hint the game could make its way to the PC and possibly virtual reality (Oculus, specifically). While this discovery doesn’t necessarily translate to the game making its way to these platforms, it does suggest that Rockstar Games might be considering bringing the game to VR. With Red Dead Redemption 2 being one of the Rockstar’s games to have full first-person support, it won’t be to difficult to imagine the game as a VR game.
Source: UploadVR